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covaxin vs covishield: detailed study of the two vaccines against covid -19

covaxin and covishield are two indigenous vaccines developed in India. This is a detailed study of both to decide which one is better?


covaxin Vs Covishield?

India has started its third phase of the covid-19 vaccination from 1st April 2021 by starting vaccination for all the citizens ageing above 45.

The first phase of the vaccination started on 16th January 2021 followed by the second phase starting from 1st March 2021.

At present India is relying on its two indigenous vaccines namely covaxin and covishield for its vaccination drive.

In this article, we will discuss in detail the different aspects of both vaccines in detail.

Key aspects of covaxin and covishield

A conventional approach has been used in developing both vaccines, here are the key features in the development of both vaccines.

Key features of covaxin:

  • Covaxin is an inactivated vaccine that contains an inactivated virus.
  • This is tried and tested method of development of a vaccine that induces immunogenicity in the individual without making infected.
  • Covaxin also claims to neutralize the UK variant & other heterogeneous strains of Covid-19.
  • Claimed efficacy of 81% after phase 3 clinical trials.

Key Features of Covishield:

  • The viral vector platform is used for the development of the Covishield.
  • ChAdOx1, a chimpanzee adenovirus is used as a carrier for the Covid-19 spike protein.
  • As like Covaxin, it induces immunogenicity in the individual without making them infected.
  • It has claimed efficacy of 79% when the second dose is administered after an interval of 4 weeks.

Storage conditions for covaxin & Covishield

This is the biggest advantage of both the vaccines as both of the vaccines are stable at a storage temperature range of 2-80 C.

This can be considered as the most suitable factor for the distribution and storage of these vaccines in Indian conditions.

Side effects of covaxin and Covishield

Side effects of covaxin:

Covaxin developed by the Bharat Biotech has claimed following side effects in its fact sheet:

  • Injection site pain / Swelling / Redness / Itching
  • Headache
  • Fever
  • Malaise/body ache
  • Nausea
  • Vomiting
  • Rashes

The company has also not denied some serious allergic reactions in rare cases after the adiministarion of the vaccine.

Side effects of Covishield:

The company has claimed following side effects in its fact shield:

  • Tenderness, pain, warmth, redness, itching, swelling or bruising at the site of injection.
  • generally feeling unwell
  • chills or feeling feverish
  • fatigue
  • Headache
  • Nausea
  • Joint Pain
  • Fever

In the rare cases (1 in 100) serious allergic reactions are reported.

• tenderness, pain, warmth, redness, itching, swelling or bruising where the injection is given

Mode of administration of covaxin & Covishield

Both of the Indian vaccines are administered through the intramuscular route which is the commonest route of the administration.

There was a lot of speculation about the Indian vaccines all over the world but with the passage of time, both vaccines are proving priceless in the fight against covid-19.

As in India still, there is no choice about the type of vaccine, so it is highly recommended that people should get themselves vaccinated at the earliest as both of the vaccines have proven their efficacy.

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