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How to Reduce the Side Effects of Wysolone (Steroids)

How to Reduce Side Effects of Wysolone

How to Reduce Side Effects of Wysolone

Why Doctors Prescribe Wysolone

Wysolone, also known as Prednisolone, is a drug widely used for immune suppression in the case of chronic allergic conditions and inflammatory diseases like rheumatoid arthritis, uvietis, asthma, autoimmune hepatitis, and Bell's palsy. It is also commonly used by opthamologists for the treatment of allergic and inflammatory conditions of the uvea, iris, conjuctiva, and optic nerves of the eyes. This medicine is also commonly prescribed to patients whose immune systems attack their own bodies because of lupus and other autoimmune diseases.

Distribution in the Body

It is well absorbed if taken orally and binds to proteins, distributing quickly throughout the body. Wysolone does pass through the placenta and also penetrates breast milk, so it is not recommended to take this medication while pregnant.


Wysolone is discharged through urine as conjugated and free metabolites. It has a one to two hour eradication half-life, meaning it takes one to two hours for half the quantity of the drug to be fully metabolized by the body.

Increased thirst and appetite are both common side effects.

Increased thirst and appetite are both common side effects.

Wysolone Side Effects

  1. Cataracts and glaucoma
  2. Peptic ulceration
  3. Slow growing rate
  4. Increase in appetite, leading to rapid weight gain
  5. Swelling of cheeks
  6. Black stool
  7. Increase in thirst
  8. Fractures and osteoporosis (Some doctors advise calcium tablets with long term use.)
You can reduce weight gain by walking twice a day.

You can reduce weight gain by walking twice a day.

How to Reduce Side Effects

Regular Testing and Doctor Visits

If you are taking this medication long term, your doctor will ask you for regular blood tests in order to keep track of and reduce side effects. These tests will include:

  • SGPT and SGOT (Tests for liver health)
  • TLC-DLC (A test for white blood cell count to check immune function)
  • HB (hemoglobin, checks oxygen in the blood)
  • Platelet count
  • R.F.T. (Checks kidney function)


  • You can reduce or maintain your weight to some extent by taking a brisk walk for 15- 30 minutes in the morning and evening.
  • Short exercises and stretching can also be beneficial to stimulate muscles and maintain your growth rate.
A diet full of fruits and leafy green vegetables will help with immune and liver function.

A diet full of fruits and leafy green vegetables will help with immune and liver function.


You should take a balanced diet, including proper nutrition. Your diet should contain:

  • Plenty of green leafy vegetables such as spinach, kale, and broccoli.
  • Fruits like red apples, bananas, grapes, and citrus fruits to maintain your natural immunity.


Before taking any medicine, make sure to consult your doctor. Some supplements that can help include:

  • Folic acid
  • Calcium
  • Liv.52 (a Himalayan product that is good for increasing the efficiency of the liver)
Make sure to take wysolone with plenty of water

Make sure to take wysolone with plenty of water

Comments on February 15, 2017:

my mother has suffered from COPD since last 3 years and doctor has prescribed the wysolone 10 mg and my mother taking the same medicine regularly from the last two years. So may know about the side effect of this medicine.

Norah fennell on January 12, 2017:

How can you get rid of the tired eyes n puffy cheecks

Scroll to Continue

chim on January 10, 2017:

I used this for long years and I am very fat now how can I reduce fat faster please give an answer on January 06, 2017:

What is the side effects of 5 mg wysolone

3 times a day for 5 days

Yogish on December 09, 2016:

Thanks very helpful....

Jeevan on November 15, 2016:

Please do not use Wysolone tablet without your doctor advice, If you quit this tablet it is more dangerous to your health... Before taking this have a word with your doctor for alternate medicine.

amarjeet on November 11, 2016:

My Endocrinologist has advised me to take wysolone-5 for the last 9 years. I was taking medicine regularly i.e. one tablet in a day, I am also taking Thyroxin for Thyroid problem, but due to several problems I am taking medicine on alternative days. Is it a harmful or I should continue to take it in the same manner.

Shashank Parmar on November 10, 2016:

I have been experiencing moderate to severe swelling since last 2 years. Apart from internal swelling in mouth, food pipe (which makes eating & breathing tough), it can literally occur anywhere externally accompanied by red rashes which gives a burning sensation if itched. I have been taking Wysolone 10 mg since last 2 years every time I feel swelling coming up (approx 3 tabs/week). My weight was 54kg from last 10 years but has gone to 57kg now. Is it a side effect & should I be concerned? Any other suggestion / advise please?

Male, 34 years, height 5'7"

shrishail k on October 31, 2016:

dear sir,

i have been suffering from wheez from the last few months consulted docter too, but it is not giving me satisfaction, while coughing my body produces sweat, i have been taking Wysolone for 2 months in between months few days i was feelign good ..but from last 2 days i am feeling the same thing

anitha on October 11, 2016:

everone has asked question but not answer for any one.

i have SLE, and rheumatoid arthritis and i am taking medicine for last ten years wysolone, HCQS, Sazo 1000mg, Folvit and methotrexate(methotrexate weekly once) i am taking medicine i maintain weight but last two months i have put on weight i dont know the reasons but all my blood reports are normal. i think i have to chose the correct diet, doctors says we can take regular food but if they give us some clear food chart i think it will be very much useful.

anand on August 28, 2016:

i am taking wysolone from past 2 months ...i am nt getting slp

sravan on August 14, 2016:

Don't use wysolone

Ananya Bhakat on July 31, 2016:

I am ananya bhakat. Before 2 months i suffered from jaundice (hepatice -e). that tine my doctor suggests me to used wysolon 10..Right now i am OK, but my cheeks become is not looking good..plz suggest mr what to do in that mail

Rajat on July 23, 2016:

Plz keep faith in doctors.. I think every medicine have some side effects.. don't worry!

meerasait. on July 08, 2016:

My wife 33 years old.she had problem

Low platelate cell.she taken daily wysolon

5mg six months.what sideeffect this.please advise me?what solution for this ?what food eat ?please advise me.

Thank you.

mdmary on July 07, 2016:

Plz...Dont take wyslone. Its a Dangerus Medicine...It Kills. Choose Alternative.

manoj kumar Arya on June 30, 2016:

my wife is suffering from fever from july 2015. Doctors diagnosed her for sacoidosis and preferred fpr 20 mg wysolone. Is it proper.

Meghal shah vora on June 01, 2016:

My mom is on wysolene 10 mg since 3 yrs.

she is already 82. But often she is suffering from several infections like infection in urine,

Stomach infections etc n she has become very weak. Please suggest some remedies for these infections. She is taking wysolene for temporal artherites.

sans on May 30, 2016:

Any allopathic medicine on chronic illness/disease functions as suppressant. In case of RA too, they prescribe immune-suppressant which supresses the immune. Remember the definition of allopathy for RA is auto-immune disease which means the immune system of our body reverses its role to attack us, thus suppress it.

I am undergoind Rheumatoid Arthristis (RA) treatment for last 9 years and have been taking allaopathy. Occassionally, I like to experiment with Ayurveda which I have learnt is about prevention and not cure. Ayurveda is not about taking pills and feeling good. It is about entire lifestyle. Pranayam and Yoga is major part of Ayurveda and should be practised very hard. Pranayam for 1.5 hrs morning and evening each will ensure control to the extent that you can do every work. I have experienced this situation after doing 3 months of pranayama for a long period.

sachin sohal on May 25, 2016:

My mother is a A.N.A positive patient . last one year and regular dose wysolone, per day 30 mg.8 weeks, at present 20 mg. continue but swelling in body . For this reason, there is mobility problems and tasteless problems . please suggest this problem solution give me on May 24, 2016:

My son is suffered from SLE since 3 and half years. Now she is alright. But doctors has suggested tabs Wysolone, HCQs, shelcall, levipill,envas and cellcept. She is taking all the tabs daily. Is it any side effects. How can i control the tablets . Please suggest any doctors, please. Now she is O K. although doctors suggested. pl give suggestion sir..

manoj kumar on May 16, 2016:

I am suffering from polyarthopathy (diagnosed by apollo chennai) since 15 years. I have taken wysolone till 2012. Now again in 2016 i am experiencing same pain problems, i don't want to take wysolone because of its side effects. suggest me some other treatement /medicine for the same. Age 39 years , sex-male

viji on April 25, 2016:

Hi, i had taken wysolone for 2 years, before 10 years. First i took 15mg then it was reduced to 10 mg after 6 months and then to 5mg after 1 year. But till now i was not able to reduce my body weight. What can i do for that ?

Srikanth Sankaran on April 02, 2016:

I am going to take this wysolone 10mg after consulting my physician Rheumatalogist whose suggestion is valuable for me.So before taking any steroid medications everyone must consult their physicians first.

major rao on March 18, 2016:

using too much Wysolone 11type of side effect will effected but it can reduce by Ayurveda blood purifier tonic

like purodil ,and vatika kasai so many

deepa on November 08, 2015:

i using wysolone for my eye vision(floating dots visibility). doctor says that i have some infection in lungs. i taking tablets from 3 months and i put on weight 5 kgs within 3 months

dinishitha on September 02, 2015:

I am 10 years old i use wysolone i started 20 mg redused 2.5 mg for every 15 days after i stop the wysolone when will I redus my weight for how many days

shashikala on August 27, 2015:

my sister is suffering with rhumatoid artherities and she is using wysolone 5/10mg per day simultaneously homeo medicine. if she cannot use wysolone her pains increases and now she is becoming fat with cheeks. she with her body weight unable to walk freely and getting waist pain. Please suggest any alternate for wysolone else suggest what to take for reducing body weight. also please explain through email the side effects with this wysolone and effect of wysolone. how long to use or whenever to use.

Geetha suresh on August 22, 2015:

Excellent inf. Pl.suggest alternate for wysolone

D Prasad on July 09, 2015:

thanks for invaluable information

VINEETA GAUTAM on June 14, 2015:

dear sir,

i have infected by ammonia solution fumes due to high volatile and temperature is nearly 48 degree. doctor suggest me wysolon 10 mg.

i m feeling weakness too much..what should i take the precaution.plz suggest me ..thank u

Gunn Hinduja on May 07, 2015:

I have rheumatoid athritis since 2006. Have one three and half year old son. Want to go for second pregnancy. Currently on methotrexate 5mg twice /sat and sun

saaz 1gm twice a day

Nagaraj on April 20, 2015:

It is very informaive

Srinivas goud on April 11, 2015:

Sir I am suffering from skin allergie from 5 years it was very itching and pain full. From2 years before I consulted a skin specialist he told me to use wysolene 5mg for 15days. But I continued it for last month. I stopped it because of I had suffered from acidic problem. There is any alternative for wysolene 5mg. To get a relief from my skin problem. or can continue these tables. Please slove my problem.

Mahek Bajaj on April 09, 2015:

I m taking Wysolone 20mg since last 20 days to cure skin ellergy as prescribed. I feel very weak n sleepy all d time n headache also. I m very afraid of its side effects as doctor has suggested to continue this tab 10mg for alternate day n after that also continue for some days.plz suggest it will be ok or something else .....

Jayanthi on April 04, 2015:


My age 30, My doctor has suggested Wysolone 5 mg for hormone issues.. i have been taking this tablet since 6 months. i gain 7 kg wgt in 6 months, my cheeks become chubby and abdomen bloated, even though i am doing physical exercise reqularlyand iam going for checkup regularly and taking blood test. My doctor told that have to take this wysolone lifelong. I felt very bad due to chubby cheeks and wgt gain. So can you please suggest me how can i reduce my weight and also tell me is there any side effects, if i continue this up to end of my life.

ganesh on March 22, 2015:

My wife got aplastic anemia docter give her medicine. Wysolone 10. Alternet days is it right or wrong.

saravanan on February 07, 2015:

I was affected by alopecia for 10 year My doctor advised to take wysolone 20 is advisable to take wat will cause if take that tablet

Kalyani on February 01, 2015:

Sir for my huband docter gave wysolone 5 for the infertility problem

Vnagasarita07 on January 21, 2015:

Sir my son aged 3 yrs complete he suffered albinum +++ for the first urine test report doctor suggest wyslone 10 mg thrice a day for 6 weeks after complete 6 weeks the dose will be reduce 25 mg for day after day already weight gain and cheeks will grow but how to control this pls advice sir but next test the report will come nil

amit singh on December 06, 2014:

My mother taking wysolone since 5 years and now she is suffering from multi disorder s like pain in lims skin allergic stomach pain and other problems now plz advice me how I can reduce side effect of it my mail id singha1059@rediffmail .com

Raj on November 16, 2014:

My daughter is suffered from SLE since 3 and half years. Now she is alright. But doctors has suggested tabs Wysolone, HCQs, shelcall, levipill,envas and cellcept. She is taking all the tabs daily. Is it any side effects. How can i control the tablets . Please suggest any doctors, please. Now she is O K. although doctors suggested. pl give suggestion sir...

p.satyanarayana on October 18, 2014:

satyanarayana psoriasis arthrities patient suffering since 20 years, and i am using whysolon 5mg per day with altraceta. i am facing heavy weight problem pls tell what can i do.

Mrs trivedi on September 26, 2014:

Is wysolone 60 per day a very high dose? I have symptoms of multiple sclerosis.pls tell me about the side effects of this dose.thnx

Ramya on September 14, 2014:

Hi I'm with RA for 10 years. And taking wysolone 5mg for 10 years with other medicines. And i'm going for checkup regularly and taking blood test as well. Now i'm going to be married in a month. I'm really worried about my pregnancy and baby. I really want to know my disease and in taken of steroids will affect my baby. Please help me to know it.