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What do Cell Biologists Do?

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What is Cell Biology?

Cell biology is the study of the fundamental unit of life - the humble cell. Cell Theory states that all living things are made up of tiny units called 'cells.' Cytology, the study of cell structure, was born in 1665 when Robert Hooke used a self-built microscope to examine thin slices of cork. The compartments he viewed under the microscope he named cellulae; Latin for 'little rooms.' (Actually what Hooke observed were not cells at all but empty cell walls that make up tree bark)

As microscopes improved and more detail was gathered about cells, Theodor Schwann began to develop cell theory. Postulated in 1839, Schwann's theory had two basic tenets:

  1. All organisms consist of one or more cells
  2. The cell is the basic unit of structure for all organisms.

In 1855, German physiologist Rudolf Virchow realised that cells could only arise by the division of other, preexisting cells - coining the term omnis cellula e cellula. This, when translated, is the third tenet of modern cell theory

3. All cells arise only from preexisting cells.

Put simply, cell biology is the study of both the basic structure of all organisms and the basic unit of reproduction. This makes an understanding of cell biology fundamental to all other aspects of biology.

Timeline of Cell Biology

DateEvent

1655

Robert Hooke observes cork through a microscope. He calls the regular, spartan boxes 'cells,' after a monk's living quarters

1674

van Leeuwenhoek discovers protozoa

1683

van Leeuwenhoek discovers bacteria

1838

Schleiden and Schwann propose Cell Theory

1855

Virchow adds to Cell theory "omnis cellula e cellula"

1931

Ruska builds first Transmission Electron Microscope

1952

DNA as hereditary material

1965

First Scanning Electron Microscope developed

1996

Sheep Cell successfully cloned

What do Cell Biologists Do?

Cell Biologists are heavily involved in fertility treatment, cancer research, neurological research (e.g. Alzheimer's), sport science, food technology, genetic engineering, embryology, development, and disease diagnosis and screening...to name but a few. With the cell being the basis of life on Earth, modern cell biology is one of the most dynamic disciplines in biology, if not in science as a whole

The modern cell biologist cannot only concern themselves with cytology (the study of cellular structure). Without the contribution biochemistry and genetics, the workings of the cell would still be a mystery. Cell biologists must therefore have a working knowledge of all three disciplines. Due to this, it is immensely difficult to pin down what an 'average' cell biologist does - it is like saying "what does a scientist do?" or "what does an engineer do?"

There are, however, some common strands. Most cell biologists will spend some of their time cell culturing (growing cells) and conducting cell assays (testing them with/for something). But there the similarities between researchers end. When I worked in a research lab for the British Heart Foundation, I worked with cells cultured from rodent hearts and HeLa cells. Other biologists in the lab were working on cancerous cell lines, whilst still others worked with bacteria.

Whilst the practical details of the job can vary, the paperwork is somewhat more generic. Experimental results must be written up and analysed. Staff meetings are often used to share recent results. Most labs require their scientists to report relevant papers from other institutions to keep staff up-to-date with the most recent developments in their field. The job therefore requires a lot of reading and researching.

The Inner Life of a Cell

What Skills does a Cell Biologist Need?

The most important traits for a prospective cell biologist are:

  • an eye for accuracy and manual dexterity - both vital for intricate lab work;
  • patience;
  • strong subject knowledge and enough insight to interpret your results;
  • excellent written and verbal communication skills;
  • competency with ICT and basic cytological techniques (cell culturing, separation, and visualisation, as well as basic cell assays)

It must be stressed that those without a firm basis in mathematics will struggle pursuing a career in cell biology. Raw data is (usually) useless; it requires some manipulation using tools such as statistics. Papers published in journals are the lifeblood of academic institutions. To understand results from other institutions, let alone publish your own, requires good mathematical knowledge. Some institutions employ dedicated statisticians, but a firm basis in stats yourself will really help you stand out from the crowd.

The other thing you need is mental toughness. Working as a research scientist you must be prepared for failure - many of your experiments will fail...or worse...come back inconclusive. Experiments can take days and weeks and, without determination, a lack of success can grind you down. This only serves to make to 'eureka' moment all the more satisfying.

What do Cell Biologists Make?

Apart from a positive contribution to society? At some point in the research into any potential job, the question of money inevitably crops up. Salaries depend on experience, whether you are working in academia or industry, how recognised you are in the field, how large a team you lead etc. Below are cell biologist wages for different levels:

Cell Biologist Salaries

UK Data from 2010 Prospects.ac.uk Survey.
US Figures supplied by 2010 US Bureau of Labor Statistics National Employment Survey

UK PositionSalary (p/a)US PositionSalary

Entry level technician (BSc)

£16,000

 

Research Scientist (MSc/MRes)

£22,000 - £27,500

 

 

Postdoc Research Associate (PhD)

£26,500 - £35,000

Entry Level (PhD)

$33,000

Senior Researcher (10yrs)

£35,000 - £57,000

Mean Salary

£71,310

Team Leader/Management

Up to £120,000pa

Top 10%

$102,190

Cell Biology - Professional Bodies

How to Become a Cell Biologist?

The road to becoming a cell biologist should be one that starts with a love of science. For research associate positions, at least a Bachelor's degree - preferably with honours - is required. If you are looking to become a research scientist-proper, a PhD is necessary. the usefulness of MSc or MPhil qualifications is debated - they can give you a useful foot on the ladder and can give you an insight into the life of a full-time researcher so you can see if pursuing this career is right for you.

With the job market being so competitive, you need something to tip you over the edge. Any work experience programmes offered during the course of your university studies are highly beneficial. If there is the option to study any modules in mathematics, statistics or computer modelling (particularly practical courses), then take them up. Skill/qualifications in bioinformatics, biostatistics and genomics are highly sought-after in the new generation of cell biologist.

Also, get as much practice and experience as you can in basic techniques in cell biology. Practice preparing samples for visualisation, preparing cell assays, sterile technique etc. Make sure you are up-to-date with the latest advancements in your chosen field and ensure your CV is finely-tuned to the job you want.

It may also be beneficial to sign up for the professional body for your chosen discipline. In the UK, the Society of Biology offers post-nominal letters to all members and awards Chartered Biologist status. Membership of such bodies is vital to network with other scientists: it may be through these contacts, rather than traditional job vacancies, that you secure your first position. Start building these networks early in University

Where Next? Cell Biology

Comments

asdfghjkl; on September 05, 2017:

LOL love it

ProAsians on October 09, 2014:

Hey TFScientist, I congratulate you for this amazing summary. I'd like to ask you a question and ask for a few tips. How can I pursue this career as a cell biologist as a grade 11 student? Is it still possible or too late? As a cell biologist are we able to create personal cures or assigned?

David Stillwell from Sacramento, California on April 29, 2012:

so true TFScientist!

Rhys Baker (author) from Peterborough, UK on April 22, 2012:

@ Marcy: I agree that Cell Biologist has a nice ring to it - it sounds more technical than perhaps the job is

@cocopreme: I was aiming for a summary - I'm glad I hit the nail on the head

@alliemacb: I think the video is the best in biology - it makes the cell look like its own little world, a self-contained, automated city

Rhys Baker (author) from Peterborough, UK on April 22, 2012:

@davenmidtown: Nature is usually first to technological advancements - the aerofoil, pneumatics, trigger traps and cloning were all seen in nature before man figured them out!

huntingintime from Kent,Washington on April 20, 2012:

Nice Hub!

Candace Bacon from Far, far away on April 20, 2012:

Very nice summary of cell biology. This is a great resource for someone who is potentially interested in cell biology as a career. Great hub!

Marcy Goodfleisch from Planet Earth on April 20, 2012:

Outstanding! I like the details you have here - so well done. It sounds like a very interesting career, and besides that, I like the sound of "Cell Biologist" - it has a flair to it.

alliemacb from Scotland on April 20, 2012:

Fascinating hub and really useful for anyone considering entering the field of cell biology. Love the video. Voted up and awesome

David Stillwell from Sacramento, California on April 20, 2012:

Hello TFScientist: Another exCELLent hub... (smile) I was looking at your table of cellular achievements and scientists who added to the field of study... 1996 successful cloning of a sheep cell.. Hello Dolly ( smile)...(slight chuckle)... I thought that female bees are born from unfertilized eggs and that male bees are formed from fertilized eggs... how is it that bees are so much more advanced... then we humans... in terms of reproduction/cloning... ds