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Chelation and Stem Cell Therapies Completely Repair the Heart

Dr. Arturo V. Estuita, MD, internist and chelationist (with stethoscope); Ms. Data, having a session in infusion chelation therapy, completes 45-session program


Antioxidants capture free radicals and reactive oxygen species

Heart disease

Chelation and stem cell therapies repair the damage done by free radicals

By Conrado D. Fontanilla

The basic problem in repairing the heart is that its muscles are irreplaceable. The common knowledge is that muscles of the cardiovascular system (heart, artery, vein, capillary) do not replace themselves. To assuage ourselves, we entertain the thought that they heal themselves in a long period of time. Other cells replace themselves in a process called apoptosis or programmed cell death. Blood cells replace themselves every 140 days.

Apoptosis is like what happens in the tail of a lizard that dries up. (You might not have seen such a tail but this is only an analogy.) The drying up is not a disease but in preparation of replacement. In place of the dried up part is a new tail part that is initiated by tissue factor. If the dried up part had an injury, that injury is thrown away when the new growth of tail gets into position. The new tail is a healthy one.

Apoptosis is different from cell death that is owing to an injury accompanied by "cellular and nuclear swelling and inflammation."

"Apoptotic cells are frequently phagocytosed (engulfed) by neighboring cells and often disappear without eliciting an inflammatory response (Saraste and Pulkki 2004)." (Pober, J.S. and W. Min. "Endothelial Cell Dysfunction, Injury and Death. The Vascular Endothelium II. 2004:137-138, parenthetical mine).

In other words, "the same person" named James Person, now aged 20 is different from the James Person when he was aged 15 years. The reason is that all his body parts had replaced themselves, except his nerves, brain, and cardiovascular system.

Back to heart disease that means “coronary heart disease” (Ornish, D., MD. Dr. Dean Ornish’s Program for Reversing Heart Disease, 1996). It is different from rheumatic heart, or arrhythmia, or heart failure, or inborn hole in the heart. Delivering blood to heart muscles is the role of coronary arteries, so-called because they wrap around the heart like a crown. The right coronary artery supplies blood to the right side. The left anterior descending artery feeds blood to the front side. The circumflex coronary artery supplies its back.

Started by free radicals, blockage develops in heart arteries. A blockage of less than 50 percent of the diameter of a major heart artery may still allow a normal flow of blood. However, when the blockage had grown over 50 percent to about 75 percent symptoms are felt like chest pain upon exertion, called angina pectoris.

Available technology

The predominant methods to correct heart disease are medications, angioplasty and coronary bypass surgery. Medications may consist of drugs: vasodilators that dilate arteries; calcium channel blocker that slow the entry of calcium into cells; beta blocker that competes with adrenaline for cell receptors; blood thinner that prevents aggregation of blood into clot; cholesterol-lowering drugs that reduce cholesterol level in the blood.

Angioplasty involves the use of thin plastic balloon inserted into an artery with a plaque and inflated to widen the narrowed artery then withdrawn; sometimes a stent (thin wire prop) is left behind. There is some risk in angioplasty. A second team is always on hand that will perform a bypass surgery in case the angioplasty operation goes awry.

Bypass surgery involves sewing in a vein (saphenous, from the leg) on the artery on the point before a plaque, bypassing the plaque, and sewing it again on the artery after the plaque. The breast is opened and the breast bone is cut to get to the heart.

There is an operative mortality rate of 2 to 5 percent of bypass surgery. “Contrary to claims of cardiovascular surgeons, bypass surgery does nothing to improve the outlook for survival, according to the Harvard report” (Cranton, E., MD. and A. Brecher. Bypassing Bypass. 1984:136).

Considered as last resort is heart transplant. It must be done within 6 hours or else the replacement heart dies. There is also a risk of rejection on the part of the recipient and on the part of the replacement heart. “About 80 percent of people who receive a heart transplant today survive for 5 years, but the procedure is not without serious risks” (Clayman, C., editor. Your Heart. 1989: 96-97). The heart of a pig is considered suitable for use to replace human heart. However, there is a risk of viral infection because the pig is a host to virus.

How about artificial heart? “All patients who have received an artificial heart have died, mostly from strokes, kidney failure, internal bleeding, and infection” (Clayman, D., editor. Your Heart. 1989:107).

Ornish program

Dr. Dean Ornish has come up with a program that he claims reverses heart disease without the use of drugs. Some of the features are change in lifestyle, exercise, maintenance and reversal diets, meditation and group support (Ornish, D., MD. Dr. Dean Ornish’s Program for Reversing Heart Disease. 1996). He reported a reduction by eight percent of blockage in four years.

Chelation therapy

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Oral chelators consist of natural ingredients, antioxidants that also chelate blockage, like vitamins A, C, and E. They bind and remove plaque, effective when the blockage is less than 50 percent of the diameter of the artery (Walker, M., M.P.D. The Miracle Healing Power of Chelation Therapy. 1984).

Another technology for use in curing heart disease is infusion chelation therapy consisting of minerals, vitamins mixed with EDTA (ethylene diamine tetra acetate), a synthetic amino acid. Early on, EDTA was used to remedy lead poisoning, up until now. It has been found to work for the cardiovascular system as well. It works within the framework of free radical theories of diseases. It erodes plaque, administered in sessions at 125 ml per session. A chelationist in the Philippines administers 30 to 60 sessions depending on the severity of occlusion. A victim of myocardial ischemia (who has angina pectoris or who had a first or second heart attack) is administered 60 sessions on the average. The patient comes back in good health condition.

New entries as of January 16,2012

This Huber has completed 34 sessions as of January 13,2012. He was diagnosed as a "good candidate of bypass surgery" in 2002 by a conventional cardiologist. From being hypertensive, suffering from occasional angina, general weakness and diagnosed as high risk at the start of infusion chelation therapy (January 2009), Dr. Arturo V. Estuita, MD his chelationist has assessed that: (1) he is no longer considered high risk, (2) his hypertension is controlled, (3) angina under normal environment (except of course, in extreme stress and fatigue) is controlled, and (4) probability of being struck by heart attack is eliminated. He is now on the maintenance program of infusion chelation, meaning one session every three months. In the treatment program he had to go for three sessions in one week. Financial considerations stretched his treatment schedule.

The conventional cardiologist had estimated that he had a 75% occlusion of at least one heart artery. Dr. Estuita has estimated that at least 30% of that occlusion had been eroded by infusion chelation therapy; therefore, he still has some 40% occlusion. This can be further cut down with more chelation sessions up to 60 sessions in all. However, theory says that blood flow is still normal if the occlusion is 50% of the diameter of the artery.

In vogue now is oral chelation therapy with EDTA. However, Dr. Estuita says infusion chelation therapy is better because it insures that the chelation solution goes direct to the arteries where the occlusions are. EDTA taken orally passes through the stomach and small intestines where absorption may be impaired, or the chelator may be partially destroyed. EDTA is a synthetic amino acid and the small intestine is very selective as to absorption. For example, if glutathione were ingested, it will be broken down into its free amino acid components, absorbed and reconstituted by the body. In fact, supplementary superoxide dismutase (SOD), the enzyme that catches the free radical superoxide, taken orally is largely destroyed by the hydrochoric acid of the stomach. It is better that the body makes its own SOD from nutrition or food.

Chelation is an affair between EDTA and minerals that can become components of a plaque like calcium apatite (different from calcium ion) that serves as the cementing agent. EDTA has six "claws" as it were, that pinch on the mineral and moves it out of the body through the liver. EDTA removes copper and iron that catalyze the formation of, respectively, alkoxy radical and hydroxyl, potent reactive oxygen species. Copper and iron are leaked by the inside wall of the artery that has an injury like atheroma, that attracts components resulting in plague (Cranton, E. MD and A. Brecher. Bypassing Bypass. 1984).

Some side benefits from chelation therapy are control of hypertension, stroke, and diabetes types I and II. End of new entries.

Some chelationists in America have established the American Academy of Medical Preventics (Cranton, E. MD and A. Brecher. Bypassing Bypass. 1984:106). A subsequent association, American College for Advancement in Medicine (ACAM) was organized (Brecher, H. and A. Brecher. Forty Something Forever. 1997).

For more information on chelation therapy you may access the Internet with the search entry, chelation therapy cranton frackelton.

Stem cell therapy

One stem cell develops into a whole human being. It starts with a totipotent stem cell (the fertilized egg); that develops into a pluripotent stem cell; that develops into a multipotent stem cell; that develops into a unipotent stem cell; that develops into adult stem cells, in that order of development. Adult stem cells develop into skin, bone morrow cell, endothelium cell, kidney, pancreas, liver, etc. (Bellomo, M. Stem Cell Divide. 2006).

“Stem cells act as spare tires in a sense because they are used by the body to give rise to young, specialized cells to replenish old ones. Stem cells can replenish their number and on receiving specific chemical signals, they can develop into specialized cells….

“For example, hematopoietic stem cells found in the blood can differentiate into neurons, glia, skeletal muscle cells, heart muscle cells and liver cells….

“It also offers the possible growing of whole organs to replace totally damaged organs using the patient’s own stem cells and thereby avoiding organ rejection” (Halos, S.C. Ph.D. Stem Cell Therapy, Significant Change Stories. 2007:97-98).

For example, hematopoietic stem cells from the cord blood or placenta can be grown to replace cancerous blood called leukemia.

The unipotent stem cell is specialized in producing and growing one kind of cell.

Editing as of Aug. 28,2013. Adult stem cells, like skin, can now be reprogrammed back to embryonic stem cells, of stage pluripotent stem cells, called induced pluripotent stem cells (iPS). Adult cell reprogramming was discovered by Shinya Yamanaka in 2006. That means embryonic stem cells that started from the zygote are no longer necessary in stem cell research. The adult stem cell is now used in stem cell therapy.

Dr. Arturo V. Estuita is now administering stem cell therapy. End of editing.

Originating from the bone marrow, the endothelium progenitor cells (EPC), stem-cell-like cells circulating in the blood, repair the inside wall of an artery (Moreno, O.R. et al. “Promoting Mechanisms of Vascular Health.” Journal of the American College of Cardiology. 2009. vol. 53, 25:2315).

But it takes a long time for such repair to occur, if at all, in the lifetime of an old patient. This could be the reason why Dr. Cranton said that the full benefit of chelation therapy comes about 90 days after completion of infusion chelation therapy. Dr. Arturo V. Estuita, my chelationist in the Philippines, recommends a maintenance chelation therapy of once every three months, partly to delay aging.

Stem cell therapy and free radical theories of disease

It should be ensured that the hematopoietic cell to grow is free from free radical damage, especially its chromosomes. It should not have been pre-aged, according to Doug Wallace, Director of Center for Molecular and Mitochondrial Medicine and Genetics (Bellomo, M., The Stem Cell Divide. 2006:184-95). Damaged chromosomes may result in mutation and new organs may show up with tumor or cancer. Dolly, the cloned sheep, might have been grown from an old stem cell that is why it did not live long, said Wallace.

Organs grown from stem cells should be protected from free radicals that cause disease. In fact, the whole body should be protected from free radicals during a lifetime since still a fetus.


A barrier in stem cell therapy might be the genetics of the mitochondria, according to Wallace. Genetic studies have focused on the 46 chromosomes of the nucleus. But the mitochondria has 37 chromosomes that are passed on by the mother. The mitochondria stays in the cytoplasma that is present only in the egg. The sperm does not have cytoplasma that is why it does not contribute any mitochondria during fertilization of the egg.

A few steps more should be taken to understand the genetics of the mitochondria. Meanwhile we can make do with the heredity that comes from the mother, and from the heredity contributed by both the mother and father through the chromosomes in the nucleus.

New entries as of April 8, 2014

Chelation therapy is safe and effective says USA

The Institutes of Health of the USA conducted a double blind randomized with control study called "Trials to Assess Chelation Therapy" (TACT). It was launched in 2002; it ended in March 2011. Results were presented at a meeting of the American Heart Association held in Los Angeles, California on November 4,2012. I discuss this study in my Hub "USA (Institutes of Helath) Has Announced Chelation Therapy as Safe and Effective." TACT costs $30 million.

Hubs on chelation therapy by conradofontanilla


conradofontanilla (author) from Philippines on July 29, 2013:


You may mention my name to Dr. Estuita to establish some commonality in understanding. His clinic is open Sunday to Friday, 8 am to 1 pm for consultations. Please bring along any result of tests she already had.

Warmest regards

Bebiber on July 29, 2013:

Thanks for the info. Will be visiting Dr. Estuita next week for consultation for my mother.

conradofontanilla (author) from Philippines on May 05, 2013:


Yes, Dr. Estuita also attends to oarta that is an artery. I am not sure about the nature of your prominent aorta. However, oarta is usually attacked by free radicals that cause inflammation. Please do not presume that this is a diagnosis of your case. Aorta can accumulate deposits resulting in narrowing or atherosclerosis that limits blood flow that in turn can result in stroke.

Deposit or plaque or atherosclerosis can be remedied by infusion chelation therapy. Dr. Estuita's clinic is now located near the crossing of Taft Ave. and Buendia ave. or Gil Puyat Ave. You may read my comments at the bottom of my Hub "A Medical Breakthrough in the Control of Hepatitis B By Chelation Therapy."

Pinky Dacuso on May 04, 2013:

May I ask if Dr. Estuita also cater with those who have prominent aorta. I got an x-ray and d radiologist remarks I have prominent aorta. Pls reply to my email

where is Dr. Estuita clinic .. dati rati nakita ko eto sa E.Rodriguez Ave. meron pa rin po ba doon?

conradofontanilla (author) from Philippines on January 16, 2012:

I am revising last sentence of the first paragraph: "To think that the unnecessary 250,000...." should be "To think that the unnecessary 25,000...."

I read somewhere that perfusion injury can be remedied with lipoic acid which is a cofactor in glutathione whose components are glutamate, cystine, cysteine, and cofactors B2, selenium, zinc and lipoic acid. The glutathione enzyme system (glutathione peroxidase, glutathione reductase, glutathione synthetase) is the lifeline of man. Glutathione peroxidase dismantles the hydrogen peroxide (formed from superoxide, a master free radical) into safe water; glutathione reductase recycles glutathione peroxidase; glutathione synthetase makes glutathione from nutrition. Superoxide is the by-product of glucose metabolism to produce energy for man.

A surgeon who snobs free radicals will not mind about perfusion injury that is caused by free radicals.

Superoxide can start hydrogen peroxide, hydroxyl, singlet oxygen, alkoxy radical, LDL-oxy (bad cholesterol), peroxynitrite (formed with nitric oxide)that act like free radicals.

conradofontanilla (author) from Philippines on December 31, 2011:

Am I glad that I got a copy of a book containing results of research done under the framework of free radical theories of disease, "The Vascular Endothelium II," edited by Salvador Moncada and Annie Higgs, published in 2006. That spurred me to write another Hub, "A Clearer, Molecular View of Rheumatic Heart." I agree with Dr. Elmer Cranton, MD that free radical theories of disease is a breakthrough in medicine in the level of the germ theory of disease inaugurated by Pasteur. I coined "free radical theories of disease," to cover several theories involving oxygen, of which I have, so far, identified and discussed 26 in all, which is part of a book I am co-authoring with Dr. Arturo V. Estuita, my chelationist. This paradigm is considered an alternative by biomedicine or conventional medicine that it is fighting it. But medical research on free radicals is now on the march that is all the better for mankind. Biomedicine has merits and several of its tenets and applications go hand in hand with free radical paradigm. To think that the unnecessary 250,000, more or less, heart bypass surgery conducted in the United States each year could be avoided with the application of chelation therapy!

There are forces aside from science and medicine and wellness that are blocking the free radical theories of disease. The strongest is the economic force. Manufacturers of equipment and pharmaceutical laboratories and manufacturers in conventional medicine protect their investments; they appropriate political power. That reminds me of Dr. Samuel S. Epstein, MD who wrote a book, "The Politics of Cancer." What would become of the heart-lung machine when stem cell and chelation therapies are opted instead of coronary bypass surgery? It would follow the hyperbaric oxygen chamber that delivers pure oxygen then land in a museum. The hyperbaric oxygen chamber still has uses, especially in countering perfusion injury after a heart attack had been diffused. It fact, in is used as an adjunct in bypass surgery in restarting the heart to counter perfusion injury in heart muscles that are devoid of superoxide dismutase owing to the absence of oxygen during surgery. Some cardiologists and heart surgeons miss this adjunct and may commit a clinical malpractice owing to incompetence or sheer ignorance.

Tina Siuagan from Rizal, Philippines on December 30, 2011:

This hub is very informative. Thank you for sharing with us the latest advancements in the treatment modalities for cardiac disorders. Happy New Year!

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